VCAC: Cellular Processes: Mitochondrial Protein Transport: Advanced Look: Matrix

Questions? Comments? Please contact Dr. Phillip McClean or Christina Johnson.

Flythrough Tour

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CELLULAR PROCESSES

Atp Synthase

Electron Transport Chain

Protein Trafficking

Protein Modification

Protein Recycling

Insulin Signaling

Constitutive Secretion

Regulated Secretion

Mitochondrial Protein Transport

Photosynthesis (Light)

Photosystem II

Mitosis

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MOLECULAR PROCESSES

Transcription

Regulated Transcription

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NATIONAL SCIENCE FOUNDATION

U.S. DEPARTMENT OF EDUCATION

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HOME > MITOCHONDRIAL PROTEIN TRANSPORT > ADVANCED LOOK > 1.) CYTOSOL > 2.) MATRIX

Mitochondrial Protein Transport : Advanced Look --> 2.) Matrix

The final steps of protein transport int the mitochondria occur in the matrix space. Clicking on each of the thumbnail images will bring up a larger, labeled version of the described scene.

To see the Flash movie for the following sequence of images, click here.

	Once inside the matrix space, the protein is again bound by a chaperone to prevent folding.
	The first chaperone then leaves as new chaperonins attach. These new chaperonins will aid in folding the protein into its final shape.
	Soon after entering the matrix, an enzyme known as signal peptidase detects the protein's signal sequence.
	Signal peptidase then cleaves the signal sequence from the protein.
	The chaperonins finish folding the protein into its final shape.
	Once folded into its final shape, the protein is now ready to preform its proper function in the organelle.