Questions? Comments? Please contact Dr. Phillip McClean or Christina Johnson.

OVERVIEW
Flythrough Tour
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MOLECULAR PROCESSES
Transcription
Regulated Transcription
mRNA Processing
mRNA Splicing
Translation
Lac Operon
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CELLULAR PROCESSES
Protein Trafficking
Protein Modification
Protein Recycling
Insulin Signaling
Constitutive Secretion
Regulated Secretion
Mitochondrial Protein Transport
Mitosis
Meiosis
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CELLULAR ENERGY CONVERSION
Atp Synthase (Gradients)
Electron Transport Chain
Photosynthesis (Light Reaction)
Photosystem II
Glycolysis (Overview)
Glycolysis (Reactions)
Citric Acid Cycle (Overview)
Citric Acid Cycle (Reactions)
Energy Consumption
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HOME > REGULATED SECRETION > ADVANCED LOOK > 1.) VESICLES
Regulated Secretion: Advanced Look --> 1.) Vesicles

The first stage of regulated secretion involved collecting large amounts of a specialized protein into secretory vesicles docked at the cell membrane awaiting a specific release signal. Clicking on each of the thumbnail images will bring up a larger, labeled version of the described scene.

To see the Flash movie for the following sequence of images, click here.

An example of a polarized cell type that engages in the regulated secretion of a specialized protein is the beta cell, a type of cell found in the pancreas that secretes insulin.

Insulin travels from the endoplasmic reticulum into the Golgi apparatus where it is packaged into transport vesicles.

Insulin-containing transport vesicles from the trans Golgi-network fuse at the cell membrane to form large secretory vesicles.

NEXT --> 2.) EXOCYTOSIS

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